I have tried all sorts of different brewing methods and here are the differences I’ve noticed.
With pour over, you are in control/responsible for a lot of variables, from the water temperature, blooming, grind size (if you’re grinding your own beans), and pouring flow.
With drip method using a traditional method, you get more consistency but less variables to play with.
I noticed a difference in richness/flavour extracted with pour over (granted you follow typical methods of blooming and slowish pour rate).
Taste is subjsubjective so I can’t speak to what is “better”, but there should be a difference in taste given the method.